IndraLab

Statements


HGS binds USP8 and SMO. 2 / 2
| 2

sparser
"It is possible that Hrs competes with USP8 for binding Smo, as Hrs and USP8 directly interact with the same domain of Smo."

sparser
"However, we found that Hrs blocks Smo phosphorylation ( xref ), whereas USP8 does not xref , suggesting that Hrs and USP8 bind Smo in different conformation."