IndraLab

Statements

OTULIN activates Wnt. 3 / 3
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"It has been reported that induction of DNA damage by chemotherapy in breast cancer results in upregulation of OTULIN that stimulates Wnt for providing chemoresistance [219] ."
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"Thus, OTULIN mediated Wnt and beta-catenin activation upon genotoxic treatments promotes drug resistance and metastasis in breast cancers."
32770022
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"OTULIN interacts with Dishevelled 2 to promote Wnt activation by suppressing the LUBAC-mediated inhibition of Wnt signaling [ 20 , 34 ]."
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