IndraLab

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Zinc atom inhibits IKBKB. 3 / 3
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"Related to this, our group has discovered that transport of Zn through the Zn transporter ZIP8 into the cytosol functions to inhibit IKKbeta in monocytes and lung tissue, thereby controlling the extent of NF-kappaB activation and inflammation in response to sepsis XREF_BIBR, XREF_BIBR."
24732911
sparser
"For example, the IκB kinase (IKK) members IKKα and IKKβ are inhibited by zinc, albeit at high concentrations of ∼0.5 µM (139)."
31305906
sparser
"For example, the IκB kinase (IKK) members IKKα and IKKβ are inhibited by zinc, albeit at high concentrations of ∼0.5 μM (139)."
31305906