IndraLab

Statements

USP15 inhibits immune response. 3 / 3
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"USP15 suppresses tumor immunity via deubiquitylation and inactivation of TET2."
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"It is thus possible that inhibition of USP15, along with targeting immunosuppressive regulators of the tumor microenvironment, may induce strong antitumor immunity."
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"Together, these findings suggest that USP15 inhibition may not only promote cancer cell apoptosis but also boost T cell mediated anti-tumor immunity."
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