IndraLab

Statements


USP7 increases the amount of NFkappaB. 2 / 2
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"Surprisingly, USP7 knockdown decreases MDM2, AKT, and NF-kappaB gene expression levels in the T47D cell line, which harbors the p53 mutation."

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"Inhibition of USP7 reduced the expression of nuclear factor kappa B (NF-kappaB), phosphorylated-NF-kappaB (p-NF-kappaB), and phosphonated inhibitor of nuclear factor kappa B (p-IkappaBalpha), and alleviated the airway mucus hypersecretion in vivo and in vitro."