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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

USP25 inhibits TRIM25. 3 / 3

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"Interestingly, USP21 inhibits both TRIM25- and RNF135-mediated antiviral response and RIG-I activation ( xref and not depicted)."

24493797

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"USP21 inhibits TRIM25- and RNF135-mediated RIG-I polyubiquitination and activation."

24493797

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sparser

"These results demonstrate that USP21 inhibits TRIM25- or RNF135-mediated RIG-I polyubiquitination and activation to negatively regulate antiviral signaling."

24493797

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

USP25 inhibits TRIM25. 3 / 3

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