IndraLab

Statements


USP25 inhibits TRIM25. 3 / 3
| 3

sparser
"Interestingly, USP21 inhibits both TRIM25- and RNF135-mediated antiviral response and RIG-I activation ( xref and not depicted)."

sparser
"USP21 inhibits TRIM25- and RNF135-mediated RIG-I polyubiquitination and activation."

sparser
"These results demonstrate that USP21 inhibits TRIM25- or RNF135-mediated RIG-I polyubiquitination and activation to negatively regulate antiviral signaling."