IndraLab

Statements


KCNH1 increases the amount of VEGF. 4 / 4
| 4

reach
"Western blot analysis showed that VEGF expression was suppressed in Ad5-Eag1-shRNA group compared with Ad5-Control-shRNA group or saline group (XREF_FIG), indicating that the anti-tumor effects of Eag1 silencing on osteosarcoma are related to decreased angiogenesis and reduced VEGF expression."

reach
"So we examined the expression level of VEGF using Western blot analysis and the results showed that Eag1 knockdown leads to reduced expression of VEGF in MG-63 and Saos-2 cells."

reach
"This result suggested that Eag1 may upregulate the expression of VEGF in OS cells, consistent with the results that cancer cells express Eag1 show significantly higher levels of VEGF secretion than controls [XREF_BIBR]."

reach
"We found that Eag1 silencing not only suppressed angiogenesis in osteosarcoma but also reduced the expression of VEGF."