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Transcriptionally active TNF increases the amount of SCN4A. 1 / 1

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"TNF-α increases Na(+) currents by accelerating the channel activation as well as increasing the expression of VGSCs in a mechanism dependent upon NF-κB and p38 MAPK signal pathways in CNS neurons. TNF-α increased Na(+) currents by accelerating the activation of VGSCs. VGSCs were up-regulated at both the mRNA and protein levels."

26112872

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IndraLab

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Transcriptionally active TNF increases the amount of SCN4A. 1 / 1

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