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Cardenolide inhibits JAK1. 1 / 1

| 1

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"Our finding that cardenolides caused JAK1 diminishment via activation of NEDD4 suppress coronaviral replication bolsters that the NEDD4 associated JAK1 degradation is a candidate subject for the development of a novel PROTAC ; and therapeutic applications could be explored based on the property of JAK1 diminishment / inhibition of the cardenolides as antivirals ."

| PMC

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IndraLab

Statements

Cardenolide inhibits JAK1. 1 / 1

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