IndraLab

Statements

Integrins binds ADAM15 and F3. 3 / 3
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"In addition to its protease ligands, the extracellular domain of TF binds several β1 integrins as well as αvβ3 and TF regulates integrin function in cell migration through TF cytoplasmic domain signaling [ xref ]."
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sparser
"The extracellular domain of full-length TF binds αvβ3 and several β1 integrin heterodimers [ xref ], and the amino-terminal domain of asTF retains high affinity interactions with integrins α6β1 and αvβ3 to regulate endothelial cell migration, tube formation, and sprouting [ xref ]."
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sparser
"Similar to Sdc-1 mode of action, spliced F3 binds to the endothelial cell integrin αvβ3 and α6β1 to evoke tumor angiogenesis via protein tyrosine kinase-2 signaling [ xref ]."
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