IndraLab

Statements

OTUB1 binds SETD7. 11 / 11
3 | 1 7
sparser
"SET7 directly interacts with OTUB1 to methylate OTUB1 on lysine 122."
36822329
sparser
"Moreover, SETD7, a lysine monomethylase, directly interacts with OTUB1 to catalyze the methylation of OTUB1 at Lys 122, disrupting the interaction between OTUB1 and the anti -ferroptosis protein ubiquitin conjugating enzyme E2 N (UBE2N/UBC13) in H1299 lung cancer cells [ xref ]."
38955112
sparser
"Taken together, these data suggest that SET7 interacts with OTUB1 to catalyze monomethylation of OTUB1 at K122."
36822329
sparser
"The deubiquitinase OTUB1 interacts with the lysine demethylase SET7 to affect the binding activity of OTUB1 to UBC13."
40959280
reach
"These data indicated that OTUB1 directly associated with SET7."
36822329
sparser
"Next, we examined whether OTUB1 interacts with SET7 by coimmunoprecipitation assay."
36822329
sparser
"These data indicated that OTUB1 directly associated with SET7."
36822329
sparser
"In addition, it appeared that the N-terminal domain (E2/UBD) of OTUB1 did not bind to SET7, while the C-terminal domain of OTUB1 could bind to SET7 ( xref , F and G )."
36822329
biogrid
No evidence text available
36822329
biogrid
No evidence text available
36822329
biogrid
No evidence text available
36822329