IndraLab

Statements

SLC6A1 activates KCNQ5. 5 / 5
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sparser
"Remarkably, Manville et al. have recently reported that the neurotransmitter γ-aminobutyric acid (GABA) and various metabolites (β-hydroxybutyric acid and γ-amino-β-hydroxybutyric acid) directly activate Kv7.3 and Kv7.5 but not Kv7.1, 2, and 4 ( xref )."
32676036
sparser
"Here, phylogenetic analysis, electrostatic potential mapping, in silico docking, electrophysiology, and radioligand binding assays reveal that the anticonvulsant binding pocket evolved to accommodate endogenous neurotransmitters including γ-aminobutyric acid (GABA), which directly activates KCNQ5 and KCNQ3 via W265."
29748663
sparser
"We recently discovered that the inhibitory neurotransmitter γ-aminobutyric acid (GABA) directly activates Kv channels KCNQ3 and KCNQ5."
31701029
sparser
"We recently discovered that the inhibitory neurotransmitter γ-aminobutyric acid (GABA) directly activates Kv channels KCNQ3 and KCNQ5."
31925247
sparser
"Remarkably, Manville et al. have recently reported that the neurotransmitter γ-aminobutyric acid (GABA) and various metabolites (β-hydroxybutyric acid and γ-aminoβ-hydroxybutyric acid) directly activate Kv7.3 and Kv7.5 but not Kv7.1, 2, and 4 ."
32676036