IndraLab

Statements



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"The simultaneous addition of apoA-I and TPCK to the lipid loaded cells induced a small, but significant decrease (p < 0.03) of p65 activation, compared to either one alone."

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"P65 (Rel A) Ser536 phosphorylation was not affected by the PI3K inhibitors but was dose-dependently attenuated by TPCK."

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"These results suggest that TPCK inhibits NF-kappaB activation by directly modifying thiol groups on two different targets : Cys 179 of IKKbeta and Cys 38 of p65 and RelA."

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"These results suggest that TPCK inhibits NF-kappaB activation by directly modifying thiol groups on two different targets : Cys 179 of IKKbeta and Cys 38 of p65 and RelA."