IndraLab

Statements

OTULIN activates GZMM. 3 / 3
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"Accordingly, Met1-Ub on RIPK2 was largely inhibited by overexpressing OTULIN and was increased by OTULIN depletion."
23806334
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"Nonetheless, OTULIN overexpression strongly impairs coprecipitation of ubiquitinated RIPK1 with NEMO in TNF treated cells, whereas small interfering RNA mediated depletion of OTULIN increases the early accumulation of Met1-Ub on RIPK1 XREF_BIBR."
25060092
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"Activation of the MAP kinases p38 and JNK1/2 was only slightly increased by OTULIN depletion, consistent with the notion that OTULIN disassembles Met1-Ub primarily involved in IKK activation."
23806334