IndraLab

Statements

USP1 inhibits cell growth. 3 / 3
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"Knockdown of USP1 by siRNA decreased B-ALL cell growth and induced apoptosis."
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"Pimozide is a USP1 inhibitor that inhibits leukemic cell growth through degradation of ID1 proteins [ xref ]."
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"Interestingly, Pimozide promoted ID1 degradation, decreased USP1 levels, and caused a dose dependent inhibition of K562 cell growth in vitro with induction of apoptosis (XREF_FIG), though at a higher drug concentrations as compared to SJB2-043."
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