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USP7 inhibits necrosis. 2 / 2
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"However, another study reported that USP7 promotes chondrocyte proliferation and inhibits apoptosis and tumor necrosis factor-α-induced inflammatory response by inhibiting the BiP-eIF2α-ATF4-CHOP signaling pathway and NF-κB/p65 signaling pathway of endoplasmic reticulum stress [34]."
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"It was found that inhibition or downregulation of USP7 could not cause cell apoptosis and necrosis of NSCLC cells by the quantified reduction in cell number."
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