IndraLab

Statements

Phorbol 13-acetate 12-myristate inhibits JUN. 7 / 7
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"This may be because UA and UA+CG were the most potent inhibitors of DMBA and TPA induced c-jun positive cells and p50 positive cells of the treatments tested."
23835587
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"Rhein inhibits TPA induced activator protein-1 activation and cell transformation by blocking the JNK dependent pathway."
12632075
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"TPA did also repress the action of c-Jun in a promoter context other than the h ME, suggesting a complex regulation by interactions of these and, probably, other TPA regulated proteins.T3 receptors (T[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
9889342
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"Although SAG Tg expression has no detectable effect on epidermis development and proliferation under unstressed conditions, it inhibits TPA induced epidermal proliferation by targeting c-Jun for degradation 164."
23528706
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"IL-1 promotes the prolonged accumulation of Jun B, whereas the cellular content of Jun B decreases dramatically after 6 hr in cells treated with only TPA."
7675040
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"When overexpressed, SAG remarkably reduced both basal and TPA induced c-Jun levels, whereas SAG small interfering RNA (siRNA) silencing increased substantially the levels of both basal and TPA induced c-Jun."
17440073
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"We further show that overexpression of Trespin in HEK293 cells enhances cell growth and prevents the inhibition of cell growth and phosphorylation of c-Jun by the phorbol ester TPA."
12651162