IndraLab

Statements

OTUB2 activates pathway. 4 / 4
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"Perhaps OTUB2 can activate the Akt pathway on its own without requiring KRT80?"
35110531
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"MKN45 cells express a high level of OTUB2 but very little Ki67 and p-Akt (Thr308), indicating that OTUB2 does not activate the Akt pathway on its own, but via KRT80."
35110531
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"As mentioned above, OTUB2 can stably activate the NF-kappaB pathway through K48 type deubiquitination of TRAF6 and maintenance of phosphorylated p65, resulting in pathological manifestations of cancer."
35309903
sparser
"Besides that, OTUB2 activates the Akt pathway, suggesting that it may be a novel therapeutic and prognostic target in GC."
35110531