IndraLab

Statements

USP19 inhibits lipopolysaccharide. 4 / 4
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"In similar assays, USP19 also inhibited LPS-induced signaling in 293-TLR4 cells (Supplementary Fig. 1b)."
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"Our study reported that lack of USP19 reversed the protective effect of low-dose LPS on inflammation in SAH mice, as well as other neurological parameters."
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"USP19 deficiency increases the production of type I interferons (IFN) and proinflammatory cytokines induced by poly(I:C) or LPS in vitro and in vivo."
31511519
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"Deficiency of USP19 increased serum cytokine levels after administration of poly(I:C) and LPS, and promoted inflammatory death caused by administration of poly(I:C) or LPS, or infection of Salmonella typhimurium."
31511519