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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

COPS5 activates helicase. 2 / 2

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"The EF-2-like GTPase Snu114 regulates Brr2 activity in a nucleotide dependent manner [XREF_BIBR] while the Jab1 and MPN domain strongly stimulates Brr2 helicase activity in vitro [XREF_BIBR]."

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"While the entire Jab1 and MPN domain stimulates SNRNP200 helicase activity, XREF_BIBR the C-terminal tail is inserted into the active site of the SNRNP200 helicase and sterically inhibits its activity."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...