IndraLab

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COPS5 inhibits Neoplasm Invasiveness. 4 / 4
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"As shown in Figure XREF_FIG, their invasiveness were significantly suppressed by knocking-down of COPS5 in both H1650 and H2228 in concert with SNAIL reduction, suggesting the important role of COPS5 in the invasiveness of lung cancers independent of their specific oncogenic mutations."
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"As shown in Fig. 3 G and H, the results shown that the knockdown of CSN5 dramatically decreased the migration and invasion abilities of ACHN cells, whereas the upregulation of ZEB1 rescued the decreas[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Jab1/CSN5 silencing may arrest cell cycle progression and inhibit invasion via decreasing the transcriptional activity of NF-κB in colorectal cancer ."
35315259
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"Additionally, Jab1/CSN5 silencing may arrest cell cycle progression and inhibit invasion via the PI3K/AKT/NF-κB signaling pathway in CRC ."
35315259