IndraLab
Statements
USP22 binds ATXN7 bound to SUPT3H, TADA3, TAF5L, SUPT7L, TAF10, ATXN7L3, TAF1A, TAF12, TAF9, TAF2, TAF8, TADA2B, SUPT20H, KAT2A, KAT2B, TADA1, SGF29, ENY2, USP22, TRRAP, and TAF6L. 1 / 1
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"Here we present the cryogenic-electron microscopy (cryo-EM) structure of human SAGA (hSAGA)|Human SAGA is a 20-subunit, 1.4-MDa complex with five functional modules (Fig. (Fig.1a):1a): a scaffolding core that includes TBP-associated factors (TAFs); a TRRAP (Transformation/Transcription domain Associated Protein) containing a phosphoinositide-3-kinase (PI3K)-related pseudoprotein kinase (ΨPIKK); a histone acetyltransferase (HAT); a deubiquitinase (DUB) and a metazoan-specific splicing (SPL) module"