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SPP1 activates TNFAIP3. 1 / 3

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"We further show that activation of NF-kappaB by OPN occurs through a unique mechanism in which intracellular OPN (iOPN) causes transcriptional downregulation of the NF-kappaB inhibitors, A20 and TNFAIP3 and ABIN1 and TNIP1, and secretory OPN (sOPN) promotes receptor mediated activation of NF-kappaB."

27050077

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SPP1 activates TNFAIP3. 1 / 3

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