IndraLab

Statements


| 9

reach
"In addition, the ingredients in SmS ( Fig. 8 ), including Berberine ( Dang et al., 2023 ; Li, Q. et al., 2021 ; Xu et al., 2021 ), Chlorogenic acid ( Zhao et al., 2022 ; Zhou et al., 2021 ), Ferulic a[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"In a CUMS depression model, ferulic acid treatment has been observed to suppress microglial activation, NF-κB signaling, and NLRP3 inflammation."

reach
"Not surprisingly, ferulic acid has been found to suppress NLRP3 dependent inflammasome formation in various cellular models and in rodents [XREF_BIBR, XREF_BIBR, XREF_BIBR, XREF_BIBR, XREF_BIBR, XREF_BIBR]."

reach
"Other studies have found that trans-ferulic acid, which is beneficial for improving the stability of vulnerable plaques, can inhibit the inflammatory response of macrophages by inhibiting the NLRP3 pathway."

reach
"Tongxinluo intervention, a kind of Traditional Chinese Medicine, altered plaque stability by increasing the level of probiotics in the gut, thereby boosting the content of beneficial metabolites, such as trans-ferulic acid, which could inhibit the NLRP3-related inflammatory pathway in plaque and stabilize plaque [80]."

reach
"As ferulic acid can bind with the binding pockets of NLRP3 inflammasome and NF-κB protein molecules [16] , we decided to evaluate whether ferulic acid inhibits NLRP3 inflammasome, at least whether NLR[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"Moreover, ferulic acid inhibited microglia activation, pro-inflammatory cytokines expression, NF-κB signaling and decreased NLRP3 inflammasome, suggesting that anti-inflammatory related mechanism was [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"However, treatment with ferulic acid suppressed the production and expression of pro-inflammatory cytokines (TNF-α and IL-1β), possibly by inhibiting the activation of the NLRP3 inflammasome, caspase-[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"[Sodium Ferulate Attenuates Oxidative Stressvia Suppressing NALP3 Inflammasome and ERK Signal Pathway]."