IndraLab

Statements


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"Postsynaptically, CALM can modulate the abundance of GluA2 at the postsynaptic membrane by influencing its endocytosis, indicating a possible role of CALM in AMPA receptor dysfunction in AD."

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"Recent studies by Muro et al. [35,37] revealed that to internalise anti-ICAM and anti-PECAM conjugates via constitutively non internalisable determinants ECs employ a novel, previously unknown internalisation pathway, which differs from clathrin- and caveoli mediated endocytosis and CAM mediated endocytosis."

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"Amiloride hinders Na +/H+ exchange in macropinocytosis and nonclassical CAM mediated endocytosis [16,17]."

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"The fact that this process takes place only in the case of multimeric ligands incubated with cells at 37degreesC, but not at 4degreesC, indicates that CAM mediated endocytosis is an active process, with close similarities to typical receptor mediated endocytosis (Muro et al., 2008)."

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"Multivalent conjugates of 100 - 300 nm diameter, consisting of antioxidant enzymes (AOE, Cat and SOD) and carrier PECAM-1 or ICAM-1 antibodies, bind to ECs, enter cells via CAM mediated endocytosis and detoxify ROS in the cell interior."

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"Anti-ICAM and ASM nanocarriers were found to enter cells by means of CAM mediated endocytosis, that is, to bypass the clathrin dependent pathway, and to traffic to lysosomes."