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BAP1 activates Leukemia. 2 / 2

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"Moreover, the mutant ASXL1 (ASXL1-MT)/BAP1 complex promotes MLL rearrangement leukemia progression by reducing the upregulation of HOXA5, HOXA7, HOXA9, and IRF8 induced by H2AK119ub1 [136]."

38931332

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"A mutant ASXL1-BAP1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia."

39752521

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Statements

BAP1 activates Leukemia. 2 / 2

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