IndraLab

Statements


USP15 inhibits INA. 2 / 2
| 2

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"These data indicated that the molecular control of USP15-mediated degradation of NEFL and INA was a posttranslational mechanism and that USP15 may control their ubiquitylation status and subsequent degradation by the proteasome."

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"In line with the results observed in 293FT cell lines (Fig. 1H), USP15-depleted SH-SY5Y cells increased ubiquitylated forms of NEFL and INA (SI Appendix, Fig. S2B)."