IndraLab

Statements


BAP1 increases the amount of H2Aub. 4 / 4
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"Our results revealed that transfection with H2Aub K119R mutant plasmid reduced the transcription and protein expression of SLC7A11 and GPX4, and overexpression of BAP1 can promote neuronal ferroptosis by regulating H2Aub levels."

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"In addition, BAP1 KO in UMSCC47 cells led to increased levels of H2Aub as compared with control cells (XREF_FIG)."

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"Therefore, BAP1 may contribute to DNA repair by regulating H2Aub levels at damage sites."

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"Few thousands genomic locations have been inferred as potentially regulated by BAP1 owing to changes of H2Aub  levels."