IndraLab

Statements


USP25 deubiquitinates RIPK1. 8 / 8
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"USP21 interacts with RIP1 and deubiquitinates RIP1 in a DUB dependent manner."

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"Ubv.21.4 CDelta2 coimmunoprecipitated with USP21 in cotrans fected human embryonic kidney (HEK) 293T cells (XREF_FIG), blocked the deubiquitination of RIP1 by USP21 (XREF_FIG), and restored NF-kappaB activation (XREF_FIG)."

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"For example, Junichiro et al. demonstrated that USP21 constitutively deubiquitinates RIP1 in vitro and in vivo [40]; and a previous study has reported that USP20 deubiquitinates TRAF6 and Tax in vivo [40]."

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"USP21 is constitutively associated with RIP1 and deubiquitinates RIP1 in vitro and in vivo."

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"A previous study showed that USP21 deubiquitylates receptor interacting protein 1, a suppressor of TNF induced NF-KB activation."

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"Ubv.21.4 blocked the deubiquitination of RIP1 by USP21 and restored NF-jB activation, showing that it acts as an inhibitor of USP21 in cells."

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"Ubv.21.4 blocked the deubiquitination of RIP1 by USP21 and restored NF‐κB activation, showing that it acts as an inhibitor of USP21 in cells."

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"Ubv.21.4 blocked the deubiquitination of RIP1 by USP21 and restored NF‐κB activation, showing that it acts as an inhibitor of USP21 in cells."