IndraLab

Statements

SCN5A activates DCM. 4 / 4
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reach
"The DCM caused by mutations in both SCN5A and ABCC9 is accompanied by cardiac arrhythmia."
21967835
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"It is also the first study describing success of antiarrhythmic drugs in regression of HF symptoms due to DCM caused by R814W mutation in SCN5A gene."
33084224
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"This case report is the first to demonstrate that a combination of SCN5A and PRKAG2 mutations can cause DCM plus MEPPC and PRKAG2 Syndrome."
35600473
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"The heterogeneity of SCN5A mutations associated with DCM, and the heterogeneity of phenotypes renders the mechanistic explanation of SCN5A mediated DCM challenging."
32927679