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USP19 activates apoptotic process. 7 / 7
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"The results showed that BAG6 knockdown effectively reversed the promotion of proliferation and suppression of apoptosis induced by USP19 overexpression (Figure 5A–F)."
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"The expression level of USP19 remained unchanged after overexpressing or knocking down the BAG6 protein, indicating that BAG6 had no impact on the protein level of USP19 (Figure 6L).3.7 USP19 promoted apoptosis through BAG6-induced ER stress in human BC cells."
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"USP19 knockdown attenuated HG+FFA-triggered growth inhibition and apoptosis promotion in HK-2 cells."
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"We also found that USP19 overexpression inhibits cell proliferation, induces apoptosis, and regulates cell‐cycle assay in TNBC cells."
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"USP19 was significantly regulated in MDA‐MB‐231 compared with the levels detected in the control groups (Figure S1F).3.2 USP19 suppressed cell proliferation and induced apoptosis of BC cell lines."
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"In CSE-treated BEAS-2B cells , USP19 knockdown reduced FUNDC1 and LC3 II / I , increased the levels of TOM20 , improved cell survival , mitochondrial membrane potential , and OCR , and inhibited apoptosis ."
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"We demonstrated that expression of USP19 inhibited proliferation and induced apoptosis in TNBC cells, as well as promoting BAG6 protein expression by deubiquitinating modification."
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