IndraLab

Statements

S9 binds OTUB1. 4 / 4
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"We used a GST-pulldown assay to evaluate the interaction between OTUB1 and NS2 in vitro."
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"Thus, OTUB1 binds NS2 directly in vitro."
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"Our study sheds light on the critical viral-host interaction between NS2 and OTUB1 that facilitates viral propagation (Figs 8 and 10), and further research into the changes in quantity and locality of OTUB1 following IAV infection may be warranted, in order to better understand how IAV utilizes host factors to enhance viral proliferation."
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"To verify the interaction between NS2 and OTUB1, we cotransfected HEK293T cells with plasmids that expressed HA-NS2 and Flag-OTUB1."
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