IndraLab

Statements

OTUB1 inhibits poly-ubiquitin chains. 2 / 2

| 2

reach

"This suggests that the formation of DNA damage induced poly-ubiquitin chains is continually suppressed by OTUB1, possibly to prevent hyper-activation of the RNF8 and RNF168 response [35 **]."

22464734

➶

reach

"Further biochemical study found OTUB1 inhibits ubiquitin transfer from E2s to acceptor ubiquitin, thus blocking the formation of poly-ubiquitin chains."

38264570

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

OTUB1 inhibits poly-ubiquitin chains. 2 / 2

INDRA sources:

Databases

Reading