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USP22 activates immune response. 4 / 4
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"Therefore, our results indicate that Rottlerin and Morusin exerts potent anti-tumor effect and enhances antitumor immunity mediated by USP22 and merits further development.In order to gain a deeper in[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
37769523
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"Inactivation of Usp22, Brd9, and Ccdc101 enhanced antitumor immunity but also led to spontaneous inflammation in some cases (96–98)."
36479127
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"Based on these observations, the authors hypothesized that USP22 inhibition could simultaneously promote anti-tumor immunity and target tumors driven by USP22 upregulation and pathogenic H2Bub1 deplet[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
34953650
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"KO of Usp22 destabilized Foxp3 and subsequently increased antitumor immunity in vivo."
35989706