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Mutated BAP1 activates Syndrome. 2 / 2
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"Whereas BAP1 mutations drive BAP1 tumour predisposition syndrome, mesotheliomas, melanomas and other neoplasms 8–11 ; ASXL1 mutations are particularly prevalent in myeloid cancers, and are associated [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"BAP1 mutation can increase the sensitivity of HNSCC to radiotherapy and lead to tumor susceptibility syndrome, which is not related to the status of high-risk human papillomavirus (HPV) and p53 tumor suppressor protein."