IndraLab

Statements

USP15 inhibits NFE2L2. 8 / 9
| 8
reach
"Taken together, these data indicate that USP15 inhibition protects podocytes from HG-induced injury by enhancing Nrf2 activation via Keap1."
34931430
reach
"USP15 negatively regulates Nrf2 through deubiquitination of KEAP1 and affects paclitaxel resistance ."
31659154
reach
"Taken together, these results further demonstrate that USP15 negatively regulates the Nrf2 antioxidant response."
23727018
reach
"Myc-USP15 inhibited the activity of Nrf2 in a concentration dependent manner (XREF_FIG)."
23727018
reach
"USP15 negatively regulates Nrf2 through deubiquitination of Keap1."
23727018
reach
"USP15 inhibits the transcriptional activity of Nrf2 and the Nrf2 dependent antioxidant response."
23727018
reach
"In accordance, the deubiquitinating enzyme USP15 negatively regulates Nrf2 through deubiquitination of Keap1 [XREF_BIBR]."
32234331
reach
"USP15 increases the degradation of Nrf2 by stabilizing the Cul3-Keap1-E3 ubiquitin ligase complex."
23727018