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Sitagliptin inhibits FOS. 2 / 2

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"In addition, sitagliptin significantly reduced the expression of osteoclast specific markers in mouse bone-marrow-derived macrophages, including calcitonin receptor (Calcr), dendrite cell specific transmembrane protein (Dc-stamp), c-Fos, and nuclear factor of activated T-cells cytoplasmic 1 (Nfatc1)."

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"Another study revealed that sitagliptin inhibits ERK, TNF-α, c-Fos, cut-like homeobox 1 and NF-κB expression in THP-1 cells, vascular endothelial cells and monocytes ( Ikeda et al., 2013 )."

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Sitagliptin inhibits FOS. 2 / 2

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