IndraLab

Statements


USP1 decreases the amount of ID2. 2 / 2
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"Usp1 deficiency resulted in a gradual loss of memory CD8 + T cells over time and reduced Id2 protein levels and proliferation of effector CD8 + T cell following reinfection."

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"It has been shown that shRNA mediated USP1 depletion reduced the levels of ID1 and ID2, resulting in p21 induced cell-cycle arrest.22 However, acute depletion of USP1 did not affect the levels of ID1 and ID2 in U2OS cells, this discrepancy could be explained by different depletion methods."