IndraLab

Statements

KCNMA1 activates HMGB1. 5 / 5
| 5
reach
"In contrast, lytic SLO doses promoted HMGB1 release independently of NLRP3 or Casp1 activation."
28533778
reach
"We tested whether sublytic SLO challenge promotes inflammasome activation by comparing Casp1 activation and HMGB1 secretion in WT, NLRP3 -/-, and Casp1 -/- BMDM treated with sublytic or lytic doses of SLO."
28533778
reach
"Thus, sublytic SLO can promote HMGB1 release and Casp1 activation in a NLRP3 inflammasome dependent manner."
28533778
reach
"Sublytic SLO Induces NLRP3 Inflammasome Activation and HMGB1 Release."
28533778
reach
"In NLRP3 -/- and Casp1 -/- BMDM, sublytic SLO promoted minor HMGB1 egress, without appreciably depleting cytoplasmic stores."
28533778