IndraLab

Statements

USP18 increases the amount of ISG15. 2 / 2

| 2

reach

"The overexpression USP18 significantly inhibited the levels of conjugated ISG15 protein and upregulated the expression of free ISG15 protein in IFNT-induced gEECs ( p < 0.05, Fig. 5 A–C)."

36934584

➶

reach

"As USP18 deconjugates ISGylation and promotes ISG15 secretion, loss of USP18 increases the intracellular level of ISG15."

36736853

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

USP18 increases the amount of ISG15. 2 / 2

INDRA sources:

Databases

Reading