IndraLab

Statements

AGFG1 binds CALM1. 4 / 4
| 4
sparser
"An FCHO1 Y635S alteration does not prevent binding of either HRB or CALM ( xref E)."
27237791
sparser
"Second, Hrb and CALM bind efficiently to only the FCHO1 μHD and neither FCHO2 nor SGIP1, despite all exhibiting robust eps15 and intersectin interactions."
22484487
sparser
"Yet the noted selectivity between FCHO1 and FCHO2/Sgip1 for HRB and CALM binding ( xref E) cannot be solely attributed to this Y635T/S dichotomy."
27237791
sparser
"Amino acid divergence between the FCHO1 and structurally related FCHO2 (53% identity) and Sgip1 (49% identity) μHDs is paralleled by differences in partner protein selectivity; FCHO2 and Sgip1 contact a subset of FCHO1 partners ( xref , xref , xref ) including EPS15 ( xref E), but only the FCHO1 μHD binds to HRB and CALM in our assays."
27237791