IndraLab

Statements

OTUB1 ubiquitinates TP53. 3 / 3

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"OTUB1 may instead interfere with ubiquitination of p53 by inhibiting the E2 enzyme UbcH5."

35608338

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"Thus, Otub1 mediates p53 ubiquitination in cells independently of its de-ubiquitinating enzymatic activity."

32532965

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"In contrast with USP7, OTUB1 may interfere with the ubiquitination of TP53 by inhibiting the MDM2 cognate E2 UBE2D1 [46]."

36551253

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

OTUB1 ubiquitinates TP53. 3 / 3

INDRA sources:

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