IndraLab

Statements

COPS6 activates lipid biosynthetic process. 3 / 3
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reach
"COP9 signalosome subunit 6 (CSN6), an oncogenic marker of CRC, increases lipogenesis via interacting with and stabilizing FASN."
37202390
reach
"Together, these results demonstrated that CSN6 and FBXW7β participated in the vicissitude of FASN’s stability.Next we performed a phenotypic rescue experiment, asking whether CSN6-FBXW7β relationship is involved in CSN6-mediated lipogenesis and cell growth in CRC cells."
37202390
reach
"CSN6-induced lipogenesis facilitates CRC tumor growth, which can be suppressed by FASN inhibitor orlistat."
37202390