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UCHL3 activates osteoblast differentiation. 6 / 6
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"Importantly , UCH-L3 deubiquitylates Smad1 and enhances osteoblast differentiation [ 73 ] ."
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"These results of increased expression of differentiation markers and down-stream target genes suggest that Uch-L3 may enhance osteoblast differentiation by elevating the stability of Smad1.To determin[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"These results suggest that the reduction of Uch-L3 decreases the active pSmad1 signal and thus reduces the osteoblast differentiation.This study showed a novel function for Uch-L3 in osteoblast differ[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"These results suggest that Uch-L3 plays a role as a modulator in the BMP2-mediated osteoblastogenesis and thus enhancing the differentiation of osteoblasts.In our previous study, we reported elevated [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Furthermore, the forced expression of Uch-L3 promoted the osteoblast differentiation, and Uch-L3 knock-down showed reduced differentiation.This study shows a novel finding that osteoblast differentiat[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"UCH-L3 activates osteoblast differentiation by deubiquitinating and stabilizing Smad1 ( Kim et al ., 2011 ) ."
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