IndraLab

Statements

TGFBR1 binds USP15. 10 / 10
5 | 5
reach
"USP15 binds to the Smad7 and Smurf2 complex and, like USP4 and USP11, deubiquitinates the TGF-beta type I receptor, thereby maintaining the stability of this receptor and enhancing TGF-beta signalling[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
27155333
reach
"Ubiquitin-specific peptidase 15 (USP15), a deubiquitinating enzyme, binds to the SMAD7-SMURF2 complex and deubiquitinates and stabilizes TGFBR1, resulting in enhanced TGF-β signaling ."
35017630
biogrid
No evidence text available
34546211
biogrid
No evidence text available
34546211
reach
"Moreover, we show that USP15 interacts with other type I BMP receptors ALK2 and ALK6, as well as TGFbeta receptor ALK5."
24850914
biogrid
No evidence text available
24850914
biogrid
No evidence text available
22344298
biogrid
No evidence text available
23973329
reach
"The interaction between USP15 and TbetaRI was detected by co-immunoprecipitation and ubiquitination assays."
34546211
reach
"Co-immunoprecipitation and ubiquitination assays revealed that USP15 interacted with TbetaRI and deubiquitinated TbetaRI."
34546211