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"However, whether BAP1 can positively regulate the transcription of RHOJ via removing the monoubiquitination of histone H2A remains to be further delineated.Regarding the regulation of BAP1 at the transcriptional level in HCC, we identified two transcription factors, CTCF and NRF1, which positively regulated BAP1 transcription by direct binding to the promoter region of BAP1."