IndraLab

Statements


Modified USP7 activates TP53. 2 / 2
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"The expression of USP7/HAUSP prevents p53 ubiquitination from Mdm2 as a p53-specific E3 ligase and increases the p53 protein stability [25]."
| PMC

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"Collectively, the data suggest that overexpression of USP7 up-regulates steady-levels of Poleta independent of p53 and suggested that Poleta, like p53, could be a substrate of USP7."