IndraLab
Statements
USP2 inhibits Interferon. 2 / 2
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2
reach
"These data together suggest that inhibition of USP2 promotes the proliferation of macrophages and dendritic cells to activate IL-22- and IFNγ-producing T cells during DSS-induced colitis.We also examined whether targeting USP2 by ML364 inhibited the dysregulation of ECM and promoted tissue repair."
reach
"Taken together, these data suggest that USP2 restricts the proliferation of myeloid cells and thereby inhibits the activation and expansion of IL-22- and IFNγ-producing T cells in the lamina propria during DSS-induced colitis.2.6
USP2 in myeloid cells inhibits immune responses to bacterial infections in the gut."