IndraLab

Statements


USP10 inhibits PTEN. 4 / 4
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"USP10 suppresses lung cancer cell invasion and growth via upregulating PTEN [22]."

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"USP10 was reported to inhibit tumor growth and inactivate mTORC1 and AKT signaling by stabilizing AMPKalpha and PTEN in HCC cells."

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"Moreover , USP10 , but not its inactive C424A deubiquitinating mutant or other deubiquitinases , abolished PTEN from K63-linked polyubiquitination mediated by TRIM25 ."

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"Moreover, USP10, but not its inactive C424A deubiquitinating mutant or other deubiquitinases, abolished PTEN from K63 linked polyubiquitination mediated by TRIM25."