IndraLab

Statements

UCHL5 decreases the amount of SNRPF. 4 / 4
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"Thus, the possible mechanism of UCH-L5 downregulates SNRPF expression may through interacting with NFRKB or other components of INO80 complex."
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"We also found that knockdown of UCH-L5 could upregulate the mRNA and protein level of SNRPF, while overexpression of UCH-L5 downregulated the mRNA and protein level of SNRPF in U87MG cells infected by Lentivirus."
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"Accordingly, we found UCH-L5 inhibited mRNA expression and protein level of SNRPF both in U87MG cells and U251 cells significantly."
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"To further confirm that UCH-L5 inhibits SNRPF expression, U87MG and U251 cells were subjected to analysis for lentivirus mediated gene knockdown and overexpression."
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